Nucleoplasmin is a nuclear protein. This protein was divided into two segments and linked to the same large cytoplasmic protein, generating two fusion proteins. After injecting these fusion proteins into a cell, one of the proteins was found in the nucleus and the other in the cytoplasm. Which of the following conclusions can be drawn from these results?

Nucleoplasmin is a nuclear protein. This protein was divided into two segments and linked to the same large cytoplasmic protein, generating two fusion proteins. After injecting these fusion proteins into a cell, one of the proteins was found in the nucleus and the other in the cytoplasm. Which of the following conclusions can be drawn from these results?

Nucleoplasmin is a nuclear protein. This protein was divided into two segments and linked to the same large cytoplasmic protein, generating two fusion proteins. After injecting these fusion proteins into a cell, one of the proteins was found in the nucleus and the other in the cytoplasm. Which of the following conclusions can be drawn from these results?



  1. The cytoplasmic protein contains a nuclear localization signal.
  2. Nucleoplasmin does not have a nuclear localization signal.
  3. One of the fusion proteins entered the nucleus by passive transport.
  4. Only one of the two fusion proteins possesses a nuclear localization signal.



Answer: Only one of the two fusion proteins possesses a nuclear localization signal.


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